Drugs That Can Cross the Blood Brain Barrier

Researchers have found that older adults taking claret pressure level-lowering medications known to cross the claret-brain barrier had improve retentivity compared to those taking other types of medicines to treat high blood force per unit area. The research published (Monday 21 June) is in the scientific journal, Hypertension.

High blood pressure or hypertension in mid-life is a known take a chance factor of dementia, which affects 850,000 people in the United kingdom. Just like the eye, the encephalon depends on a good blood supply to work properly and having loftier claret force per unit area tin can put this supply at risk.

What our expert said

Dr Rosa Sancho, Caput of Research at Alzheimer'southward Research UK, said:
"There are things we tin all do to assistance our brains as we get older. Keeping our blood pressure in check is one factor in our power to control to effort and help prevent dementia.

"This new inquiry looked to see whether blood pressure lowering drugs able to pass the blood-brain-barrier – an important structure in the encephalon – led to a benefit in retention and thinking skills but didn't necessarily look at dementia. They found that those taking bulwark-crossing drugs had a pocket-size merely not insignificant improvement in memory, while those taking drugs that were not able to cantankerous the barrier displayed better attention skills.

"Millions of people in the Uk are prescribed blood pressure medications to support their cardiovascular wellness. Doctors will prescribe the most appropriate medication for their patients based on their individual circumstances. Anyone who has any concerns about the medications they are taking should speak to their GP.

"Inquiry shows that twoscore% of dementia cases are linked to factors we may exist able to influence, and the all-time evidence suggests that we can wait afterwards our brain past keeping cholesterol levels in check, maintaining a healthy weight, keeping physically and socially active, not smoking and drinking within the recommended limits. At the same time, we must continue to invest in inquiry that can take us closer to a world free of the fear, heartbreak and harm dementia brings."

Want to read more?

You lot can read the full research paper here.

Just as we can protect other areas of our health, nosotros can take steps to go along our brains healthy and reduce our gamble of developing dementia later in life. Discover out about keeping your blood pressure in check hither. Information technology forms part of Alzheimer's Research UK'southward Think Brain Wellness entrada, a celebration of everything our incredible brains do for us and a guide to the simple things nosotros can practise to protect them in render.

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Source: https://www.alzheimersresearchuk.org/blood-pressure-drugs-that-can-cross-the-blood-brain-barrier-have-impact-on-memory/